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Microcrystalline Cellulose

Microcrystalline Cellulose Powder

Availability: In stock

From £18.90

Availability: In stock

From £18.90

Key Benefits of Microcrystalline Cellulose Powder:

  • Microcrystalline Cellulose Powder is also known as MCC.
  • MCC Powder is an excellent choice for the manufacturer of tablets using direct compression methods.
  • MCC can carry a high amount of active ingredients.
  • Cellulose Powder is one of the best tablet binders on the market and is very cost effective.
  • Unfortunately, due to maufacturers ceasing making Microcrystalline Cellulose Powder for the foreseeable future do to the COVID-19 crisis, the product is in short supply and we have had to increase our prices to reflect the current market.
  • Shipped within 1 working day subject to stock.
Our Microcrystalline Cellulose Powder is a fine off white powder with spherical granules to provide flowability. This product's certificate of analysis can be viewed within the product pictures above.

Microcrystalline cellulose is widely used in pharmaceuticals, primarily as a binder/diluent in oral tablet and capsule formulations where it is used in both wet-granulation and direct-compression processes (1–7) In addition to its use as a binder/diluent, microcrystalline cellulose also has some lubricant(8) and disintegrant properties that make it useful in tableting. Microcrystalline cellulose is also used in cosmetics and food products.

Uses of Microcrystalline Cellulose. Use Concentration (%)
Adsorbent 20—90
Antiadherent 5—20
Capsule Binder/Diluent 20—90
Tablet Disintegrant 5—15
Tablet Binder/Diluent 20—90

Microcrystalline cellulose is a purified, partially depolymerized cellulose that occurs as a white, odorless, tasteless, crystalline powder composed of porous particles.

Microcrystalline cellulose is manufactured by controlled hydrolysis with dilute mineral acid solutions of a-cellulose, obtained as a pulp from fibrous plant materials. Following hydrolysis, the hydro cellulose is purified by filtration and the aqueous slurry is spray dried to form dry, porous particles of broad size distribution.

Microcrystalline cellulose is an excipient of outstanding merit and remains the most widely used direct compression excipient serving as a strong dry binder, tablet disintegrant, an absorbent, filler or diluent, a lubricant, and anti-adherent.

Microcrystalline Cellulose is generally considered as the diluent having the best binding properties and is recognized as one of the preferred Directly compressible binders. It is used as a binder/diluent in oral tablet and capsule formulations including both wet granulation and direct compression processes. It also has some lubricant and disintegrant properties which are useful in direct tableting. Small amounts of MCCs are able to efficiently bind other materials, especially poorly table active pharmaceutical ingredients. Microcrystalline Cellulose Powder exhibits a high dilution potential, whereas the broad particle size range provides optimum packing density and coverage of other materials

Microcrystalline Cellulose Powder has been very well known as the most compressible of all direct compression fillers which has the highest dilution potential and capacity. It is defined as the amount of active ingredient that a diluent can successfully carry in the direct compression method. This property can be explained by the basis of the physicochemical nature of MCC particles, which are held together by hydrogen bonds. Microcrystalline Cellulose particles are deformed plastically under compaction forces to yield an extremely large number of clean surfaces brought in contact during this deformation, forming a strong compact even under low compression forces.

Microcrystalline Cellulose is a self-disintegrating binder with low lubricant requirements with regard to its dry binding properties due to the extremely low coefficient of friction and its very low residual die wall pressure. However, these properties do not replace the need for true disintegrants and lubricants as an addition when MCC is used in a tablet formulation such as magnesium stearate and silicon dioxide.

Other advantages of Microcrystalline Cellulose Powder include broad compatibility with various APIs, physiological inertness, ease of handling, and ease of supply for manufacturer

Please note that orders over 2kg will be packaged in a clear re-sealable bag.

Advisory Information
The products sold by Blackburn Distributions are not intended to diagnose, treat, restore, correct or modify any functions in human beings. They are solely intended to help maintain & support a healthy lifestyle. The claims presented have not been evaluated by the FDA or the MHRA. We recommend that you seek advice from a fully qualified health care professional before consuming any of these products especially if you are taking other medications or pregnant. Discontinue use and consult a doctor if any adverse reactions occur. Not intended for use by persons under the age of 18. Keep out of reach of children. Store in a cool, dry place.
Microcrystalline Cellulose Ingredients

Microcrystalline Cellulose 99.43%

Suitable For

Non-vegetarians, vegans, vegetarians.



Customer Reviews 45 item(s)

M.d.l.m posted on 27 Nov, 2020
very good product
Ravenblak_K4liva posted on 24 Sep, 2020
Verified Purchase
Peter posted on 18 Aug, 2020
Verified Purchase
Fast delivery and good price, packaged in a 20kg bag discount on second order

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